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1

Common Mechanism of Toxicity: A Case Study of Organophosphorus Pesticides

Beth E. Mileson, Janice E. Chambers, W.L. Chen, Wolf Dettbarn, Marion Ehrich, Amira T. Eldefrawi, David W. Gaylor, Karen Hamernik, Ernest Hodgson, Alexander G. Karczmar, Stephanie Padilla, Carey N. Po

Journal:

Toxicological Sciences

Year:

1998

Language:

english

File:

PDF, 118 KB

english, 1998

2

Myopathy-inducing drugs and fast axoplasmic transport

Norman A. Ranish, Wolf-D. Dettbarn

Journal:

Experimental Neurology

Year:

1977

Language:

english

File:

PDF, 405 KB

english, 1977

3

Acute tabun toxicity; biochemical and histochemical consequences in brain and skeletal muscles of rat

Ramesh C. Gupta, Gary T. Patterson, Wolf-D. Dettbarn

Journal:

Year:

1987

Language:

english

File:

PDF, 660 KB

english, 1987

4

Prevention of diisopropylphosphorofluoridate (DFP)-induced skeletal muscle fiber lessions in rat

Gary T. Patterson, Ramesh C. Gupta, Karl E. Misulis, Wolf-D. Dettbarn

Journal:

Year:

1988

Language:

english

File:

PDF, 489 KB

english, 1988

5

Distinction between action on acetylcholinesterase and on acetylcholine receptor in axons

Wolf-D. Dettbarn

Journal:

Biochimica et Biophysica Acta (BBA) - Specialized Section on Biophysical Subjects

Year:

1964

Language:

english

File:

PDF, 152 KB

english, 1964

6

Carbofuran-induced oxidative stress in slow and fast skeletal muscles: prevention by memantine and atropine

Dejan Milatovic, Ramesh C. Gupta, Andrzej Dekundy, Thomas J. Montine, Wolf-D. Dettbarn

Journal:

Year:

2005

Language:

english

File:

PDF, 166 KB

english, 2005

7

iso-OMPA-induced potentiation of soman toxicity in rat

Ramesh C. Gupta, Wolf -D. Dettbarn

Journal:

Archives of Toxicology

Year:

1987

Language:

english

File:

PDF, 512 KB

english, 1987

8

Characterization of acetylcholinesterase molecular forms in slow and fast muscle of rat

Douglas E. Groswald, Wolf-D. Dettbarn

Journal:

Neurochemical Research

Year:

1983

Language:

english

File:

PDF, 542 KB

english, 1983

9

A histochemical study of the distribution of choline acetyltransferase and acetylcholinesterase activity in sensory ganglia and nerve roots of the bullfrog

Alvin M. Burt, Wolf-Dietrich Dettbarn

Journal:

Journal of Molecular Histology

Year:

1972

Language:

english

File:

PDF, 1.59 MB

english, 1972

10

Involvement of nitric oxide in myotoxicity produced by diisopropylphosphorofluoridate (DFP)-induced muscle hyperactivity

Ramesh C. Gupta, Dejan Milatovic, Wolf-D. Dettbarn

Journal:

Archives of Toxicology

Year:

2002

Language:

english

File:

PDF, 1.12 MB

english, 2002

11

Nitric oxide modulates high-energy phosphates in brain regions of rats intoxicated with diisopropylphosphorofluoridate or carbofuran: prevention byN-tert-butyl-α-phenylnitrone or vitamin E

Ramesh C. Gupta, Dejan Milatovic, Wolf D. Dettbarn

Journal:

Archives of Toxicology

Year:

2001

Language:

english

File:

PDF, 488 KB

english, 2001

12

Seizure-induced changes in energy metabolites and effects of N-tert-butyl-α-phenylnitrone (PNB) and vitamin E in rats

Ramesh C. Gupta, Dejan Milatovic, Marko Zivin, Wolf-D. Dettbarn

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2000

Language:

english

File:

PDF, 348 KB

english, 2000

13

RELATIONSHIP BETWEEN CHOLINE AVAILABILITY AND ACETYLCHOLINE SYNTHESIS IN DISCRETE REGIONS OF RAT BRAIN

Lynn Wecker, Wolf-D. Dettbarn

Journal:

Journal of Neurochemistry

Year:

1979

Language:

english

File:

PDF, 551 KB

english, 1979

14

AXOTOMY INDUCED CHANGES IN CHOLINERGIC ENZYMES IN RAT NERVE AND MUSCLES

Norman A. Ranish, Tomaz Kiauta, Wolf-D. Dettbarn

Journal:

Journal of Neurochemistry

Year:

1979

Language:

english

File:

PDF, 631 KB

english, 1979

15

Differential Effect of Denervation on Free-Radical Scavenging Enzymes in Slow and Fast Muscle of Rat

Kohtaro Asayama, Wolf D. Dettbarn, Ian M. Burr

Journal:

Journal of Neurochemistry

Year:

1986

Language:

english

File:

PDF, 503 KB

english, 1986

16

Comparison Between the Effects of Botulinum Toxin-Induced Paralysis and Denervation on Molecular Forms of Acetylcholinesterase in Muscles

Janez Sketelj, Neva Črne-Finderle, Dušan Sket, Wolf-D. Dettbarn, Miro Brzin

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 771 KB

english, 1993

17

Distinction between Sodium and Potassium in Change in Permeability effected by Lipid-soluble Analogues of Acetylcholine

DETTBARN, WOLF D.

Journal:

Year:

1959

File:

PDF, 219 KB

1959

18

Effect of Curare on Conduction in Myelinated, Isolated Nerve Fibres of the Frog

DETTBARN, WOLF D.

Journal:

Year:

1960

File:

PDF, 212 KB

1960

19

Modification of Acetylcholinesterase during Adaptation to Chronic, Subacute Paraoxon Application in Rat

Dejan Milatovic, Wolf-D. Dettbarn

Journal:

Toxicology and Applied Pharmacology

Year:

1996

Language:

english

File:

PDF, 138 KB

english, 1996

20

Diisopropylphosphorofluoridate-Induced Cholinergic Hyperactivity and Lipid Peroxidation

Zhen P. Yang, Wolf-D. Dettbarn

Journal:

Toxicology and Applied Pharmacology

Year:

1996

Language:

english

File:

PDF, 114 KB

english, 1996

21

Cytochemical localization of cholinesterase activity at the giant synapse of the squid

Miro Brzin, Virginia M. Tennyson, Wolf-Dietrich Dettbarn

Journal:

Histochemistry and Cell Biology

Year:

1975

Language:

english

File:

PDF, 1.55 MB

english, 1975

22

Role of carboxylesterases in the prevention and potentiation of N-methylcarbamate toxicity

Ramesh C. Gupta, Wolf-D. Dettbarn

Journal:

Chemico-Biological Interactions

Year:

1993

Language:

english

File:

PDF, 493 KB

english, 1993

23

Mechanisms of toxicity and tolerance to diisopropylphosphorofluoridate at the neuromuscular junction of the rat

Ramesh C. Gupta, Gary T. Patterson, Wolf-D. Dettbarn

Journal:

Toxicology and Applied Pharmacology

Year:

1986

Language:

english

File:

PDF, 802 KB

english, 1986

24

Role of uptake of [14C]valine into protein in the development of tolerance to diisopropylphosphorofluoridate (DFP) toxicity

Ramesh C. Gupta, Wolf-D. Dettbarn

Journal:

Toxicology and Applied Pharmacology

Year:

1986

Language:

english

File:

PDF, 811 KB

english, 1986

25

Differences in central and peripheral neural actions between soman and diisopropyl fluorophosphate, organophosphorus inhibitors of acetylchlinnesterase

Karl E. Misulis, Mary Ellen Clinton, Wolf-D. Dettbarn, Ramesh C. Gupta

Journal:

Toxicology and Applied Pharmacology

Year:

1987

Language:

english

File:

PDF, 655 KB

english, 1987

26

Neuronal oxidative injury and dendritic damage induced by carbofuran: Protection by memantine

Ramesh C. Gupta, Snjezana Milatovic, Wolf-D. Dettbarn, Michael Aschner, Dejan Milatovic

Journal:

Toxicology and Applied Pharmacology

Year:

2007

Language:

english

File:

PDF, 543 KB

english, 2007

27

Alterations in cytochrome c oxidase activity and energy metabolites in response to kainic acid-induced status epilepticus

Dejan Milatovic, Marko Zivin, Ramesh C Gupta, Wolf-D Dettbarn

Journal:

Year:

2001

Language:

english

File:

PDF, 1.83 MB

english, 2001

28

Involvement of nitric oxide in kainic acid-induced excitotoxicity in rat brain

Dejan Milatovic, Ramesh C Gupta, Wolf-D Dettbarn

Journal:

Year:

2002

Language:

english

File:

PDF, 268 KB

english, 2002

29

Prevention of kainic acid seizures-induced changes in levels of nitric oxide and high-energy phosphates by 7-nitroindazole in rat brain regions

Ramesh C. Gupta, Wolf-D Dettbarn

Journal:

Year:

2003

Language:

english

File:

PDF, 246 KB

english, 2003

30

Nitrone spin trapping compound N-tert-butyl-α-phenylnitrone prevents seizures induced by anticholinesterases

Marko Zivin, Dejan Milatovic, Wolf-D Dettbarn

Journal:

Year:

1999

Language:

english

File:

PDF, 1.51 MB

english, 1999

31

Different role of carboxylesterases in toxicity and tolerance to paraoxon and DFP

Wolf-D. Dettbarn, Zhen P. Yang, Dejan Milatovic

Journal:

Chemico-Biological Interactions

Year:

1999

Language:

english

File:

PDF, 96 KB

english, 1999

32

Atypical effect of some spin trapping agents: reversible inhibition of acetylcholinesterase

Dejan Milatovic, Zoran Radic, Marko Zivin, Wolf-D Dettbarn

Journal:

Free Radical Biology and Medicine

Year:

2000

Language:

english

File:

PDF, 190 KB

english, 2000

33

Lipid peroxidation and changes in cytochrome c oxidase and xanthine oxidase activity in organophosphorus anticholinesterase induced myopathy

Zhen P. Yang, Wolf-D. Dettbarn

Journal:

Journal of Physiology-Paris

Year:

1998

Language:

english

File:

PDF, 391 KB

english, 1998

34

Demonstration of phospholipid splitting as the factor responsible for increased permeability and block of axonal conduction induced by snake venom. I. Study on lobster axons

Eleonora Condrea, Philip Rosenberg, Wolf-D. Dettbarn

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1967

Language:

english

File:

PDF, 1.14 MB

english, 1967

35

Increased cholinesterase activity of intact cells caused by snake venoms

Philip Rosenberg, Wolf-D. Dettbarn

Journal:

Biochemical Pharmacology

Year:

1964

Language:

english

File:

PDF, 649 KB

english, 1964

36

Penetration of neostigmine, physostigmine, and paraoxon into the squid giant axon

Miro Brzin, Wolf-Dietrich Dettbarn, Philip Rosenberg

Journal:

Biochemical Pharmacology

Year:

1965

Language:

english

File:

PDF, 456 KB

english, 1965

37

The action of acetylcholine and cholinesterase inhibitors on single axons of the lobster

Wolf-Dietrich Dettbarn, Eva Bartels

Journal:

Biochemical Pharmacology

Year:

1968

Language:

english

File:

PDF, 832 KB

english, 1968

38

Action of acetylcholine in the presence of organophosphates on single axons of the lobster

Eva Bartels, Miro Brzin, Wolf-Dietrich Dettbarn

Journal:

Biochemical Pharmacology

Year:

1969

Language:

english

File:

PDF, 340 KB

english, 1969

39

Acetylcholine—A possible mechanism for the depolarization response in giant axons of the lobster circumesophageal connective

Theodore B. Hoekman, Wolf-D. Dettbarn

Journal:

Biochemical Pharmacology

Year:

1971

Language:

english

File:

PDF, 474 KB

english, 1971

40

Acetylcholine, choline acetyltransferase and cholinesterases in motor and sensory nerves of the bull frog

Frank Welsch, Dennis E. Schmidt, Wolf-Dietrich Dettbarn

Journal:

Biochemical Pharmacology

Year:

1972

Language:

english

File:

PDF, 783 KB

english, 1972

41

Effect of parathion and its metabolites on calcium uptake activity of rat skeletal muscle sarcoplasmic reticulum in vitro

Neal Binder, Erwin J. Landon, Lynn Weckhr, Wolf-D. Dettbarn

Journal:

Biochemical Pharmacology

Year:

1976

Language:

english

File:

PDF, 546 KB

english, 1976

42

Central cholinergic mechanisms underlying adaptation to reduced cholinesterase activity

Lynn Wecker, Philip L. Mobley, Wolf-D. Dettbarn

Journal:

Biochemical Pharmacology

Year:

1977

Language:

english

File:

PDF, 474 KB

english, 1977

43

Acetylcholine, choline acetyltransferase and cholinesterases in the rat heart

Robert L. Stanley, Jim Conatser, Wolf-D. Dettbarn

Journal:

Biochemical Pharmacology

Year:

1978

Language:

english

File:

PDF, 318 KB

english, 1978

44

Hydrolysis of tetriso by an enzyme derived from Pseudomonas diminuta as a model for the detoxication of O-ethyl S-(2-diisopropylaminoethyl) methylphosphonothiolate (VX)

Francis C.G. Hoskin, John E. Walker, Wolf-D. Dettbarn, James R. Wild

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 553 KB

english, 1995

45

Diisopropylphosphorofluoridate-induced muscle hyperactivity associated with enhanced lipid peroxidation in vivo

Zhen P. Yang, Jason Morrow, Aiping Wu, L.Jackson Roberts II, Wolf-D. Dettbarn

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 611 KB

english, 1996

46

Action of lipid-soluble quaternary ammonium ions on the resting potential of myelinated nerve fibers of the frog

Wolf D. Dettbarn

Journal:

Biochimica et Biophysica Acta

Year:

1959

Language:

english

File:

PDF, 613 KB

english, 1959

47

New evidence for the role of acetylcholine in conduction

Wolf D. Dettbarn

Journal:

Biochimica et Biophysica Acta

Year:

1960

Language:

english

File:

PDF, 655 KB

english, 1960

48

“Sucrose gap” technique applied to single-nerve-fiber preparation

Wolf-D. Dettbarn, Floyd A. Davis

Journal:

Biochimica et Biophysica Acta

Year:

1962

Language:

english

File:

PDF, 210 KB

english, 1962

49

The active form of local anesthetics

Wolf D. Dettbarn

Journal:

Biochimica et Biophysica Acta

Year:

1962

Language:

english

File:

PDF, 248 KB

english, 1962

50

Ultrastructural changes at the motor end-plate produced by an irreversible cholinesterase inhibitor

Michael B Laskowski, William H Olson, Wolf-D Dettbarn

Journal:

Experimental Neurology

Year:

1975

Language:

english

File:

PDF, 9.07 MB

english, 1975